Searchable abstracts of presentations at key conferences on calcified tissues

ba0005p53 | Bone development/growth and fracture repair | ECTS2016

Effect of bioactive glass-ceramic scaffold associated with bone marrow - or adipose-derived mesenchymal stem cells on bone formation under osteoporotic conditions

Freitas Gileade , Lopes Helena , Almeida Adriana , de Souza Luiz , Siessere Selma , Regalo Simone , Beloti Marcio , Rosa Adalberto

In this study, we evaluated the effect of the association of a bioactive glass-ceramic scaffold (Biosca) with mesenchymal stem cells derived from either bone marrow (BM-MSCs) or adipose tissue (AT-MSCs) on bone formation in calvarial defects of osteoporotic rats. Wistar rats were submitted to bilateral ovariectomy (OVX) or only to the surgical stress (Sham), under approval of the Committee of Ethics in Animal Research. After 5 months, 5-mm unilateral calvarial defect was creat...